SymSitive* is a soothing ingredient for sensitive skin. With its neurosensory activity, SymSitive* provides instant and long-lasting relief from stinging, burning, and itching. Skin discomfort like tingling, burning and itching is characterized by a hyperresponsiveness of sensory neurons and stimulation of the thermoreceptor TRPV1 (capsaicin receptor). 

The Nobel Prize in Physiology and Medicine 2021 was awarded to David Julius and Ardem Patapoutian for the discovery of temperature receptor such as TRPV1.

SymSitive* acts on the Nobel Prize awarded mode of action of TRPV1 actively soothes the feeling of tingling, itching and burning.

*registered trademark of Symrise, Germany

Ceramides are important lipids in the hydrolipid film (which protects the external layers of skin). Produced naturally in healthy skin, they strengthen the skin barrier, helping to prevent moisture loss due to evaporation and keeping out irritants that can cause inflammation and itching. When skin’s Ceramide levels fall the skin barrier is impaired. Skin can start to lose water and become dry and irritated.
Eucerin uses synthetic Ceramides that are biologically-identical and that enhance skin’s natural barrier – locking in moisture and preventing dryness and irritation.

Licochalcone A is a potent anti-inflammatory and antioxidant active that is derived from the roots of the Chinese licorice plant Glycyrrhiza inflata. Licochalcone A protects cells from oxidative stress mediated by UV and blue light (HEVIS).

Licochalcone A is able to activate anti-inflammatory, antioxidant and detoxifying enzymes. These enzymes protect the skin cells from damage induced by oxidative stress, like lipid peroxidation and DNA as wells as protein damage. Licochalcone A is able to soothe irritated skin and redness.